譜析（上海）生物科技有限公司優(yōu)勢供應(yīng)：S. aureus Topoisomerase IV ATPase kit(金黃色葡萄球菌拓?fù)洚悩?gòu)酶IV atp酶試劑盒)
2019/10/12 14:30:09
這些試劑盒可用于檢測潛在的atp酶抑制劑的效果。例如，香豆素類藥物，如novobiocin，通過競爭性地抑制ATP的水解來抑制拓?fù)洚悩?gòu)酶IV的作用，從而防止超卷曲。這些檢測是基于微滴定板的，因此大量的化合物可以在相對較短的時間內(nèi)被篩選出來。它們還可以提供比終點(diǎn)測定更多的信息的連續(xù)測定。
These kits can be used to test the effects of potential ATPase inhibitors. For example, the coumarin drugs such as novobiocin inhibit the action of topoisomerase IV by competitively inhibiting the hydrolysis of ATP thus preventing supercoiling.
These assays are microtitre plate-based and thus large numbers of compounds can be screened in a relatively short period of time. They also continuous assays which can provide more information than an end point assay.
優(yōu)勢供應(yīng)產(chǎn)品：
| Cat No. | Product |
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| ATPSAT001 | Kit for 100 ATPase assays |
For determination of DNA-dependent ATPase activity; contains E. coli topoIV, buffers, ATP, PK-LDH, PEP, NADH and linear pBR322 DNA substrate. |
